Transoral laser surgery

Removal of tumours of the larynx and throat through the mouth, under a microscope, with a laser, leaving no incision in the neck.

Plate VII

At a glance

Who it is for
Adults with early tumours of the voice box or throat, and with selected benign lesions of the larynx
Anaesthesia
General anaesthesia
Hospital stay
Same day or one night
First step
A consultation with your endoscopy findings, biopsy result and imaging

Anatomy · Plate VII

Transoral laser surgery, seen from the side

  1. Operating microscopeGives a magnified view of the larynx; the laser beam is guided under it.
  2. LaryngoscopeA tube passed through the open mouth that gives a straight view of the voice box.
  3. Laser beamRemoves the tumour under magnification and seals small vessels as it cuts.
  4. Vocal cordsThe tumour or lesion is removed here, under the microscope.
  5. Trachea (windpipe)The airway below the vocal cords. No cut is made in the skin of the neck.

Simplified drawing, not to scale.

Transoral laser surgery (transoral laser microsurgery) treats tumours of the voice box and throat from the inside, through the mouth, without an incision in the neck. It combines an operating microscope, a laryngoscope that holds the mouth and throat open, and a carbon dioxide laser that cuts tissue precisely while sealing small blood vessels.

What it is

The technique is used for early cancers of the vocal cords and of other parts of the larynx and lower throat, for precancerous lesions, and for some benign conditions such as papillomas or scarring that narrows the airway. The tumour is removed with a narrow margin of healthy tissue, so that as much of the normal larynx as possible is preserved. Larger tumours, or tumours that cannot be exposed through the mouth, are treated with open surgery or radiotherapy instead.

Who it is for

Adults with a small or early cancer of the larynx or throat confirmed by biopsy, adults with a suspicious lesion of the vocal cords, and selected adults with benign lesions of the larynx or airway. The mouth must open, and the neck bend back, far enough for the larynx to be reached.

Symptoms and diagnosis

Persistent hoarseness is the usual reason a vocal cord lesion is found. Examination with a flexible endoscope in the consultation room shows the lesion and the movement of the vocal cords, and stroboscopy or narrow-band imaging can add detail. A biopsy under anaesthesia confirms the diagnosis, and CT or MRI is used when deeper spread is possible.

How the operation is done

Under general anaesthesia, a laryngoscope is passed through the mouth and fixed in position so that the larynx is seen through the operating microscope. The laser beam is guided under high magnification, and the tumour is removed in one piece or in a few pieces, which are sent to the pathologist so that the margins can be assessed. Because the beam seals small vessels as it cuts, bleeding and swelling are usually slight. The operation is usually short, and a breathing opening in the neck is not normally needed.

Recovery

Most people go home the same day or the next morning and can drink and eat soft foods within hours. The throat is sore for a few days, and the voice is hoarse until the surface heals over a few weeks. Voice rest is advised at first, followed by gentle use; voice therapy is arranged when it will help. Follow-up endoscopies check healing and watch for any recurrence.

How Prof. Hafız works

Transoral laser surgery is one of the focus areas of Prof. Hafız’s practice, alongside laryngeal cancer surgery and airway surgery, and he has contributed a chapter on powered instruments in ear, nose and throat surgery to a Turkish textbook. Whether a tumour is suitable for the laser, and what the alternatives are, is assessed at the consultation and explained together with the expected effect on the voice.

What to expect

  1. Before

    • Examination with a flexible endoscope in the consultation room.
    • A biopsy under anaesthesia; CT or MRI when deeper spread is possible.
  2. On the day

    • General anaesthesia; a laryngoscope through the mouth and the operating microscope.
    • The laser removes the tumour through the mouth, usually with little bleeding or swelling, and with no cut in the skin.
  3. After

    • Home the same day or the next morning; drinks and soft foods within hours.
    • Voice rest at first; the voice usually clears as the surface heals over a few weeks.
    • Follow-up endoscopies check the healing.

Questions patients ask

Is laser surgery less effective than an open operation?

For suitable early tumours, guidelines (NICE NG36) list laser surgery among the standard treatments; its effect on voice and swallowing depends on the tumour. The choice depends on the site and size of the tumour and on how well it can be exposed through the mouth.

Will I have a scar?

The operation is performed entirely through the mouth, so no cut is made in the skin of the neck.

What will my voice be like afterwards?

The voice is hoarse while the area heals and usually improves over a few weeks. The final quality depends on how much of the vocal cord had to be removed; voice therapy can help.

References

  1. Cancer of the upper aerodigestive tract: assessment and management in people aged 16 or over. National Institute for Health and Care Excellence (NICE guideline NG36). 2016. Available from: nice.org.uk/guidance/ng36 [cited ].
  2. Endoscopic cordectomy. A proposal for a classification by the Working Committee, European Laryngological Society. European Archives of Oto-Rhino-Laryngology. 2000. doi:10.1007/s004050050228.
  3. Surgery through the mouth for laryngeal cancer (transoral surgery). Cancer Research UK. 2024. Available from: cancerresearchuk.org/about-cancer/laryngeal-cancer/treatment/surgery/laser-surgery [cited ].
  4. Symptoms of laryngeal cancer. NHS. 2025. Available from: nhs.uk/conditions/laryngeal-cancer/symptoms [cited ].
  5. Suspected cancer: recognition and referral (NG12). National Institute for Health and Care Excellence. 2015. Available from: nice.org.uk/guidance/ng12 [cited ].

Talk it through with Prof. Hafız

Consultations at Selenium Plaza, Beşiktaş, Monday to Saturday. Write on WhatsApp or call the practice.